Epilepsy Intermediate of Dimethadione
DMO; Nortrimethadione; Dimethadione; Eupractone ;
2,4-Oxazolidinedione, 5,5-dimethyl- ;
Mainly intermediate of epilepsy products
In the treatment of seizures, antiepileptic drugs are of particular importance. Antiepileptic drugs can eliminate or reduce seizures in two ways. One is to affect central neurons to prevent or reduce their pathological excessive discharge; the other is to raise the excitation threshold of normal brain tissue and reduce the spread of lesion excitement. Prevent relapse of epilepsy. The anti-epileptic drugs synthesized before the 1960s, such as: phenytoin, carbamazepine, ethosuximide, sodium valproate, etc., are called old antiepileptic drugs, of which phenobarbital, phenytoin, carbamazepine, 5, 5-Dimethyloxazolidine-2,4-dione is a widely used first-line antiepileptic drug.
(1) Hydantoins: phenytoin sodium, mephenytoin, ethylphenytoin, etc.
(2) Acetylamides: carbamazepine
(3) Barbiturates: phenobarbital, primidone, amobarbital, etc.
(4) Succinimides: such as ethylsuccinamine, methylsuccinamine, phenylsuccinamine, etc.
(5) Diketones: such as trimethyldiketone, methyl ethyl ketone, Dimethadione;
(6) Side chain fatty acids, such as sodium valproate;
(7) Acetylureas: such as phenylacetylurea, phenylbutyric urea
(8) Benzodiazepines: such as diazepam, clonazepam, nitrazepam
(9) Sulfonamides: such as acetazolamide, sulmet
(10) Hormones: such as adrenocorticotropic hormone, dexamethasone, prednisone
(11) Others: such as paraaldehyde, chloral hydrate, lidocaine, caffeine, bromide, mipalin hydrochloride