The most commonly used alcohol disinfectants are ethanol and isopropyl alcohol, which can coagulate proteins and cause the death of microorganisms. It is a medium-efficiency disinfectant that can kill bacterial propagules and destroy most lipophilic viruses. Isopropyl alcohol is mostly used for skin disinfection, hand disinfection, and medical instruments such as ophthalmoscopes, microscope eyepieces and objective lenses, ultrasound probes, stethoscopes, etc. The actual use concentration is usually 70%. Isopropyl alcohol has a greater ability to dissolve lipids than alcohol, so it can have a better disinfection effect.
1. Isopropyl alcohol is its common name. Its official ingredient is dimethyl methanol, because it contains two groups of methyl groups, which greatly enhances its lipophilicity. It is a good hydrophilic and lipophilic amphoteric alcohol. Due to its strong permeability, its contact ability against bacteria and molds has been correspondingly enhanced.
2. Alcohol generally refers to a 75% ethanol medical aqueous solution, which has a set of ethyl groups. The penetration of ethyl groups is weaker than that of methyl groups, which also causes the performance gap between the two to widen further. Please refer to it.
In addition, because of this characteristic, IPA is more suitable for RNA isolation than ethanol. The mechanism of alcohol disinfection is mainly that alcohol can dissolve lipid substances in the bacterial cell wall, causing the dissolution of intracellular substances, thereby killing bacteria. Isopropyl alcohol has a greater ability to dissolve lipid than alcohol, so it can have a better disinfection effect.
Item | Technical requirements | Result | Result |
Sensory properties | Colorless transparent liquid, with acetone and alcohol similar smell, no mechanical impurities | Colorless transparent liquid with similar odor of acetone and alcohol, no mechanical impurities | Pass |
Packing volumes | Not less than 95% of the scalar specification | 20L/drum | Pass |
PH | 2020.6.8 | 6.8 | Pass |
IPA content | ≥60%（V/V） | 71%（V/V） | Pass |
Validity | ≥12month | 12 | Pass |
Project (microbiological indicators) | standard | ||
Used for hand sanitizing and surgical hand sanitizing | GB/27950 | Pass | |
For skin disinfection | GB/27951 | Pass | |
Used for surface disinfection of common objects | GB/27952 | Pass | |
Used for disinfection of medical instruments | GB/27949 | Pass | |
Item | Bacteria inhibitive rate | ||
Staphylococcus aureus（ATCC10231） | ≥90% | ||
coliform（8099） | ≥90% | ||
Candida albicans（ATCC6538） | ≥90% |
