Ethyl Trans-4-oxobutenoate For Minodronic Acid

Ethyl Trans-4-oxobutenoate For Minodronic Acid

Ethyl trans-4-oxobutenoate is one of the important intermediates of minodronic acid.
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Osteoporosis

Osteoporosis, known as the "silent killer", is a quiet epidemic. When it comes to osteoporosis, everyone’s first reaction is “calcium deficiency”. In fact, this is a “misunderstanding”. In fact, osteoporosis is caused by various reasons. Metabolic bone disease that causes a decrease in bone strength and a high risk of fracture. It is related to lack of exercise, vitamin D and other nutrients and various endocrine and metabolic disorders.

In recent years, osteoporosis has been trending towards a younger age. At the same age, I suffer from osteoporosis, and I often feel that I will break a bone when I sneeze. If I neglect exercise in my youth, I often eat picky or diet, and the diet structure is not balanced, leading to calcium in the diet. Low intake, thin body, and bad lifestyle habits such as smoking and drinking will cause osteoporosis, muscle strength will decrease, affect joint flexibility, and easily fall and fracture.

Minodronic acid is a new drug for the treatment of osteoporosis, which can strongly inhibit the absorption of osteoclasts and osteoclasts, reduce the conversion of bone cells, and can antagonize the osteolysis caused by myeloma and tumors . Ethyl trans-4-oxobutenoate is one of the important intermediates of minodronic acid. Minodronic acid inhibits the activity of farnesyl pyrophosphate (FPP) synthase in osteoclasts, inhibits bone resorption of osteoclasts, reduces bone turnover, and has the effect of preventing and treating osteoporosis. This product has low cost and high profit. 


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