Cognitive and behavioral problems are very common in children with epilepsy and are especially common in refractory epilepsy. Including mental disorders, learning difficulties, autism, behavioral abnormalities, attention deficit hyperactivity disorder, etc. These cognitive and neurodevelopmental problems can affect the quality of life of children with epilepsy, such as affecting children's daily life behavior, The ability to express words, interpersonal skills, these effects may always accompany the patient to become a persistent long-term adverse effect.
In general, cognitive impairment and neurodevelopmental problems in children with epilepsy are mainly attributed to the seizure itself and the anti-epileptic drugs used. For example, the cause of epilepsy, what kind of seizures, what type of epilepsy, the age of the initial onset, the frequency of episodes, the location of epileptic foci, which anti-epileptic drugs have been taken, and whether they are combined.
In order to enable parents of children to detect cognitive and behavioral problems in children with epilepsy, early identification and early intervention are necessary. The location of epilepsy lesions is often closely related to the type of cognitive impairment. The type of cognitive impairment is usually caused by epilepsy at the corresponding site. However, the specific clinical manifestations are many and require careful observation and identification. Frequent seizures, poor symptom control, can increase the degree of cognitive impairment and neurodevelopmental delay. And we have observed in many clinical cases that even if the patient's seizures have been controlled and become non-excited, some cognitive behavioral disorders will continue.
Cognitive neurological disorders can affect children's learning, life and future employment, and may become a regret and burden for patients' lives. However, unfortunately, these problems are often overlooked and missed, even parents and parents are lacking. Pay attention to it. Even some comorbidities, such as attention deficit hyperactivity disorder, are not treated even if diagnosed. Screening with correct and routine cognitive behavioral assessments is necessary to provide patients with long-term benefits in life, study, and work. In addition, 5,5-Dimethyloxazolidine-2,4-dione is also one of the main raw materials for antiepileptic drugs.