Method For Preparing Ethanolamine O-phosphate Compound

- Aug 30, 2019-

O-Phosphorylethanolamine CAS 1071-23-4 suppliers said that O-Phosphocolamine compounds are widely used in biotechnology, medicine and other fields, and can also be used as feed additives, special lubricants, etc.

O-Phosphorylethanolamine suppliers told us that the disclosed method and process for the synthesis of O-Phosphorylethanolamine CAS 1071-23-4 compounds are mainly based on phosphoric acid and ethanolamine, and the two are first formulated into a certain concentration solution by using a solvent. After the mixture of the two is reacted in a solvent, the Phosphorylcolamine is obtained by filtration, and finally dehydrated at a high temperature in an organic solvent to obtain an ethanolamine amine; or in an aromatic hydrocarbon (such as benzene, toluene, xylene, etc.), a bicyclic hydrocarbon, a halogenated hydrocarbon, and a high boiling point. Phosphoric acid and ethanolamine are reacted in an organic solvent such as an ether and a ketone, and then subjected to azeotropy, high-temperature water removal, purification, etc. to obtain an ethanolamine amine, such as US 2,730,542; Tetrahedron Letters, (24), 1913-1916, 1975; 196501. The method has the problems of single raw material, complicated process, many steps, long cycle, low yield (44%~80%), many by-products, low purity, high cost, serious three wastes and the like.

Ethanolamine O-phosphate manufacturers propose a new method for the preparation of Ethanolamine O-phosphate compounds. By using water as a solvent, the method has high yield, wide source of raw materials, low production cost, no three wastes, simple and safe process, and short production cycle. The product produced is of high purity.

Adding an ethanolamine or ethanolamine solution to one of phosphorus pentoxide, phosphoric acid solution, phosphorus oxychloride or phosphorus oxychloride solution at a certain reaction temperature to obtain a reaction mixture; and then subjecting the reaction mixture to direct temperature-programmed vacuum drying Thereafter, phosphoric acid ethanolamine or phosphoethanolamine hydrochloride is obtained; the reactant may be first dissolved in a certain amount of water, and then ethanolamine or ethanolamine solution may be added; the mass ratio of the reactant to a certain amount of water is 1:1 to 100.