The Application Of N-vinylcaprolactam In Biomedical Materials

- Oct 28, 2019-

N-Vinyl Caprolactam manufacturers understand that copolymers synthesized from vinyl caprolactam (VC) and N-isopropylacrylamide (MPVN) and N-n-propyl acrylamide (NNPAM) have a low critical solution temperature (LCST) and are water soluble. Sexual and non-adhesive features, a new type of liquid embolization material for endovascular embolization of cerebral arteriovenous malformation (AVM), which can be used for further animal experiments.

  Poly N-Vinyl-e-caprolactam can be used in variable temperature replacement chromatography. The so-called variable temperature replacement chromatography is a chromatographic separation of the introduction of smart polymers into proteins, resulting in a new type of temperature-dependent chromatography. Small changes in external conditions can change the molecular structure of smart polymers:

  From a hydrophilic, loosely crimped structure to a more hydrophobic, tightly globular structure, or vice versa.

  This property can be used to regulate the interaction between polymer molecules and chromatographic media. Poly n-vinylcaprolactam has a critical phase transition temperature of around 35 degrees Celsius and can be combined with Cibarcron Blue (a dye ligand). The researchers applied this polymer-modified Blue Sepharose to purify lactate dehydrogenase in pork.